Posted in Cell Biology

Adult Stem Cell Therapies: Alternatives to Plasticity by Mariusz Z. Ratajczak

By Mariusz Z. Ratajczak

This well timed quantity explores numerous suggestions for tissue and organ regeneration utilizing stem cells remoted from grownup tissues. It discusses substitute causes of stem mobilephone plasticity in addition to present medical effects with grownup stem telephone treatments. It examines the presence of capability pluripotent stem cells in grownup tissues, paracrine results of stem mobilephone remedies, and involvement of exosomes and microparticles into saw phenomena. Fifteen chapters, all written by means of famous leaders in their fields, concentrate on various issues together with wire blood and hematopoietic stem cells, dermis and tissue organ regeneration, very small embryonic-like stem cells, and phone remedies in cardiology, neonatology, and neurology. Edited by way of Dr. Mariusz Ratajczak, an across the world identified expert in grownup stem phone biology, Adult Stem phone remedies: possible choices to Plasticity is a vital addition to the Stem mobile Biology and Regenerative Medicine series.

Show description

Read or Download Adult Stem Cell Therapies: Alternatives to Plasticity PDF

Similar cell biology books

Spirulina Platensis Arthrospira: Physiology, Cell-Biology And Biotechnology

Spirulina Platensis, a blue-green algae, has been well-known and used all over the world as a standard resource of protein within the nutrients undefined. The makes use of and mass cultivation of this algae have risen considerably because of an elevated realizing of its organic structures. ; this article includes particular descriptions of either the biology and the biotechnological makes use of of Spirulina Platensis.

RNA Processing: A Practical Approach

As post-transcriptional occasions turn into more and more famous as serious legislation websites of gene expression in eukaryotic cells, study curiosity in RNA processing has grown progressively more severe. RNA Processing: a pragmatic process, on hand in volumes, bargains special counsel on all significant facets of the topic.

Molecular Aspects of Transport Proteins

The improvement of molecular organic suggestions and their program within the box has given a brand new size to the realm of membrane delivery. the combo of biochemical (site-specific reagents), molecular organic (site-directed mutagenesis) and genetic methods of which this quantity offers a variety of examples together with biophysical strategies as X-ray research and NMR will ultimately bring about an entire elucidation of the mechanism of motion of those shipping proteins.

Animal Cell Culture: Essential Methods

This can be a accomplished learn consultant that describes either the most important new concepts and extra proven equipment. each bankruptcy discusses the advantages and obstacles of some of the methods after which presents chosen tried-and-tested protocols, in addition to a plethora of fine functional suggestion, for fast use on the bench.

Extra info for Adult Stem Cell Therapies: Alternatives to Plasticity

Sample text

Exp Hematol 39:495–505 105. Havens AM, Shiozawa Y, Jung Y, Sun H, Wang J, McGee S et al (2013) Human very small embryonic-like cells generate skeletal structures, in vivo. Stem Cells Dev 22:622–630 106. Mikhail MA, M’Hamdi H, Welsh J, Levicar N, Marley SB, Nicholls JP et al (2008) High frequency of fetal cells within a primitive stem cell population in maternal blood. Hum Reprod 23:928–933 107. Habich A, Jurga M, Markiewicz I, Lukomska B, Bany-Laszewicz U, Domanska-Janik K (2006) Early appearance of stem/progenitor cells with neural-like characteristics in human cord blood mononuclear fraction cultured in vitro.

1007/978-1-4939-1001-4_3, © Springer Science+Business Media New York 2014 35 36 M. Adamiak et al. transplantation into a mismatched host, and their ability to produce large quantities of homogenous tissue or cells during proliferation and differentiation [8]. Due to volume restriction, single UCB unit typically offers a limited number of cells. However, a growing interest in the scientific community focuses on methods to develop safe and reliable technologies for ex vivo expansion, effective cryopreservation of UCB-derived SCs as well as pooling of SPCs derived from few UCB units [9].

1). While murine BM-derived VSELs have been extensively characterized, more work is still required to better characterize these small cells at the molecular level in humans. Importantly, several independent groups worldwide have provided evidence on the existence of primitive VSEL or VSEL-like SCs residing in human UCB, BM, mobilized peripheral blood, and other human specimens, reporting their unique features and indicating their potential role in tissue and organ rejuvenation, longevity and regeneration [41, 44–49].

Download PDF sample

Rated 4.72 of 5 – based on 27 votes